---How amazing it is that astronauts are exploring outer space! 

  ---t’s a challenge, I guess,         man against nature. 

A. of             B. for               C. by              D. about

A


解析:

考查介詞。應(yīng)答句中的I guess是插入語(yǔ),因此所填介詞與challenge連用,表所屬,用of,選A。

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