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He has made another wonderful discovery, _____ I think is of great importance to science.   
A．whichB．whatC．whenD．that
A
考察定語從句。Which指代先行詞discovery在句中作主語。What不是定語從句的關系詞，when是關系副詞，that不能引導非限制性定語從句。故A正確。
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