He tried his best to solve the problem, _______difficult it was.
A．no matterB．no matter howC．whateverD．a(chǎn)lthough
B

試題分析：考查讓步狀語從句。No matter +特殊疑問詞引導(dǎo)讓步狀語從句，意為：無論…；意為后面接形容詞difficult，所以使用how.而不是what.句意：無論問題有多難，他都全力以赴地解決它。故B正確。
點評：no matter特殊疑問詞只能引導(dǎo)讓步狀語從句；特殊疑問詞ever既可引導(dǎo)時間狀語從句也可以引導(dǎo)名詞性從句。
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