解:(1)51.27-8.66-1.34,
=51.27-(8.66+1.34),
=51.27-10,
=41.27;
(2)88×125,
=11×8×125,
=11×(8×125),
=11×1000,
=11000;
(3)28.4-3.96-1.04+4.6,
=(28.4+4.6)-(3.96+1.04),
=33-5,
=28;
(4)64×64+36×64,
=64×(64+36),
=64×100,
=6400;
(5)58×99,
=58×(100-1),
=58×100-58×1,
=5800-58,
=5742;
(6)35×4×25×20,
=(35×20)×(4×25),
=700×100,
=70000.
分析:(1)根據(jù)減法的性質(zhì)簡(jiǎn)算;
(2)先把88分解成11×8,再運(yùn)用乘法結(jié)合律簡(jiǎn)算;
(3)運(yùn)用加法結(jié)合律以及減法的性質(zhì)簡(jiǎn)算;
(4)運(yùn)用乘法分配律簡(jiǎn)算;
(5)先把99分解成100-1,再運(yùn)用乘法分配律簡(jiǎn)算;
(6)運(yùn)用乘法交換律和結(jié)合律簡(jiǎn)算.
點(diǎn)評(píng):此題是考查四則混合運(yùn)算,要仔細(xì)觀察算式的特點(diǎn),靈活運(yùn)用一些定律進(jìn)行簡(jiǎn)便計(jì)算.